Drugs & MedicationsHeart DiseasePreventive Medicine


Substituting regular table salt (100% sodium chloride) with salt substitute (62% sodium chloride, 25% potassium chloride, 12.5% flavorings) reduced the chances of developing high blood pressure by 40% over a two-year period. So says a study reported in the Journal of the American College of Cardiology. Those who continued regular salt developed high blood pressure much more frequently. This finding has translated into a powerful statement suggesting this change be made for most people. 

The folks in this study were all over age 55. Substituting pseudo salt for real salt resulted in a drop of 7.1 mm Hg systolic and 1.9 mm Hg diastolic in those patients. Those folks who were given regular salt had increases of 7.0 mm Hg systolic and 2.1 mm Hg diastolic. Researchers studied people over age 55, but think salt substitute would benefit younger adults, as well. 

Salt substitute needs to be used carefully, however, in patients with chronic kidney disease. Potassium chloride found in the salt substitute is easily retained in the blood stream of patients with failing kidneys. High potassium can lead to fatal arrhythmias. These folks all have high blood pressure so eliminating both regular or substitute salt is advisable in these patients.  

Reference: Brooks M. Salt Substitute Reduces Risk for New Hypertension Medscape Clinical Digest. 2024 Apr 24.

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  1. I used salt substitute for several years, and ultimately found that I used more of the substitute making the NA CL about what I would have used with salt alone !! LOL

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